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Hedgehog pathway maintains cell survival under stress conditions, and drives drug resistance in lung adenocarcinoma

Hedgehog (HH) pathway plays an important role in embryonic development, but is largely inactive in adult except for tissue repair. Aberrant activation of HH pathway has been found in a variety of cancer types. In non-small cell lung cancer, however, the role and importance of HH pathway remain contr...

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Detalles Bibliográficos
Autores principales: Lin, Erh-Hsuan, Kao, Yu-Rung, Lin, Chih-An, Kuo, Ting-Yu, Yang, Sheng-Ping, Hsu, Chiung-Fang, Chou, Teh-Ying, Ho, Chao-Chi, Wu, Cheng-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029693/
https://www.ncbi.nlm.nih.gov/pubmed/27015549
http://dx.doi.org/10.18632/oncotarget.8253