Cargando…

Hedgehog pathway maintains cell survival under stress conditions, and drives drug resistance in lung adenocarcinoma

Hedgehog (HH) pathway plays an important role in embryonic development, but is largely inactive in adult except for tissue repair. Aberrant activation of HH pathway has been found in a variety of cancer types. In non-small cell lung cancer, however, the role and importance of HH pathway remain contr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Erh-Hsuan, Kao, Yu-Rung, Lin, Chih-An, Kuo, Ting-Yu, Yang, Sheng-Ping, Hsu, Chiung-Fang, Chou, Teh-Ying, Ho, Chao-Chi, Wu, Cheng-Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029693/ https://www.ncbi.nlm.nih.gov/pubmed/27015549 http://dx.doi.org/10.18632/oncotarget.8253

Ejemplares similares

YAP1 is essential for tumor growth and is a potential therapeutic target for EGFR-dependent lung adenocarcinomas
por: Lee, Ting-Fang, et al.
Publicado: (2017)

Sonic Hedgehog Signaling in Organogenesis, Tumors, and Tumor Microenvironments
por: Jeng, Kuo-Shyang, et al.
Publicado: (2020)

CYP17A1 Maintains the Survival of Glioblastomas by Regulating SAR1-Mediated Endoplasmic Reticulum Health and Redox Homeostasis
por: Lin, Hong-Yi, et al.
Publicado: (2019)

Gankyrin activates the hedgehog signalling to drive metastasis in osteosarcoma
por: Wang, Chongchong, et al.
Publicado: (2021)

High O-linked N-acetylglucosamine transferase expression predicts poor survival in patients with early stage lung adenocarcinoma
por: Lin, Yi-Cheng, et al.
Publicado: (2018)

Stromal hedgehog signaling maintains smooth muscle and hampers micro-invasive prostate cancer
por: Yang, Zhaohui, et al.
Publicado: (2017)

The Serum Concentrations of Hedgehog-Interacting Protein, a Novel Biomarker, Were Decreased in Overweight or Obese Subjects
por: Chou, Hsuan-Wen, et al.
Publicado: (2021)

E-cadherin expression in the tumor microenvironment of advanced epidermal growth factor receptor-mutant lung adenocarcinoma and the association with prognosis
por: Chang, Yu-Ping, et al.
Publicado: (2023)

Nitric oxide maintains cell survival of Trichomonas vaginalis upon iron depletion
por: Cheng, Wei-Hung, et al.
Publicado: (2015)

Low-Dose Nicotine Activates EGFR Signaling via α5-nAChR and Promotes Lung Adenocarcinoma Progression
por: Wang, Mong-Lien, et al.
Publicado: (2020)

The Survival of Septic Patients with Compensated Liver Cirrhosis Is Not Inferior to That of Septic Patients without Liver Cirrhosis: A Propensity Score Matching Analysis
por: Chang, Ya-Chun, et al.
Publicado: (2022)

Hedgehog actively maintains adult lung quiescence and regulates repair and regeneration
por: Peng, Tien, et al.
Publicado: (2015)

Ligand-dependent hedgehog signaling maintains an undifferentiated, malignant osteosarcoma phenotype
por: Vaghjiani, Vijesh G., et al.
Publicado: (2023)

Feedback Regulation of O-GlcNAc Transferase through Translation Control to Maintain Intracellular O-GlcNAc Homeostasis
por: Lin, Chia-Hung, et al.
Publicado: (2021)

Fabrication and Characterization of a Tunable In-plane Resonator with Low Driving Voltage
por: Kao, Pin-Hsu, et al.
Publicado: (2009)

Myocardium-derived conditioned medium improves left ventricular function in rodent acute myocardial infarction
por: Leu, Steve, et al.
Publicado: (2011)

NKX6-1 mediates cancer stem-like properties and regulates sonic hedgehog signaling in leiomyosarcoma
por: Su, Po-Hsuan, et al.
Publicado: (2021)

Impact of Body Mass Index on the Survival of Patients with Sepsis with Different Modified NUTRIC Scores
por: Tsai, Yi-Hsuan, et al.
Publicado: (2021)

Immune profiles and clinical outcomes between sepsis patients with or without active cancer requiring admission to intensive care units
por: Fang, Wen-Feng, et al.
Publicado: (2017)

Landscape of Mitochondria Genome and Clinical Outcomes in Stage 1 Lung Adenocarcinoma
por: Raghav, Lovely, et al.
Publicado: (2020)

Comparing Mortality Risk Predictive Ability of Different Scoring Systems in Cirrhotic Patients with Bacteremia
por: Hung, Chi-Chieh, et al.
Publicado: (2020)

EGFR mutation, smoking, and gender in advanced lung adenocarcinoma
por: Tseng, Chien-Hua, et al.
Publicado: (2017)

The buccohypophyseal canal is an ancestral vertebrate trait maintained by modulation in sonic hedgehog signaling
por: Khonsari, Roman H, et al.
Publicado: (2013)

The association of macronutrients in human milk with the growth of preterm infants
por: Lin, Yi-Hsuan, et al.
Publicado: (2020)

Development and validation of immune dysfunction score to predict 28-day mortality of sepsis patients
por: Fang, Wen-Feng, et al.
Publicado: (2017)

Sonic Hedgehog signaling pathway as a potential target to inhibit the progression of hepatocellular carcinoma
por: Jeng, Kuo-Shyang, et al.
Publicado: (2019)

Fucosyltransferase 4 shapes oncogenic glycoproteome to drive metastasis of lung adenocarcinoma
por: Lu, Hsuan-Hsuan, et al.
Publicado: (2020)

Hedgehog signaling establishes precursors for germline stem cell niches by regulating cell adhesion
por: Lai, Chun-Ming, et al.
Publicado: (2017)

Brain metastases in patients with non-small cell lung cancer: the role of mutated-EGFRs with an exon 19 deletion or L858R point mutation in cancer cell dissemination
por: Hsiao, Shih-Hsin, et al.
Publicado: (2017)

Protease‐activated receptor 1 drives and maintains ductal cell fates in the premalignant pancreas and ductal adenocarcinoma
por: Tekin, Cansu, et al.
Publicado: (2021)

Generating a robust prediction model for stage I lung adenocarcinoma recurrence after surgical resection
por: Wu, Yu-Chung, et al.
Publicado: (2017)

Glutathione peroxidase 4 expression predicts poor overall survival in patients with resected lung adenocarcinoma
por: Liu, Chao-Yu, et al.
Publicado: (2022)

Litchi seed extract inhibits epidermal growth factor receptor signaling and growth of Two Non-small cell lung carcinoma cells
por: Chung, Yuan-Chiang, et al.
Publicado: (2017)

Correction: the buccohypophyseal canal is an ancestral vertebrate trait maintained by modulation in sonic hedgehog signaling
por: Khonsari, Roman H, et al.
Publicado: (2013)

Application of a 72 h National Early Warning Score and Incorporation with Sequential Organ Failure Assessment for Predicting Sepsis Outcomes and Risk Stratification in an Intensive Care Unit: A Derivation and Validation Cohort Study
por: Hsu, Chih-Yi, et al.
Publicado: (2021)

Factors related to overweight and obese populations maintaining metabolic health
por: Lin, Yi-Hsuan, et al.
Publicado: (2022)

The hedgehog’s trick for escaping immunosurveillance: The molecular mechanisms driving myeloid-derived suppressor cell recruitment in hedgehog signaling-dependent tumors
por: Xie, Jingwu
Publicado: (2014)

Hedgehog can drive terminal differentiation of amniote slow skeletal muscle
por: Li, Xiaopeng, et al.
Publicado: (2004)

Functional genetic variant of WW domain-containing oxidoreductase (WWOX) gene is associated with hepatocellular carcinoma risk
por: Lee, Hsiang-Lin, et al.
Publicado: (2017)

Expression of Survivin and Cortactin in Colorectal Adenocarcinoma: Association with Clinicopathological Parameters
por: Lee, Ying-Yu, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_97b74em5066oh0p2tvkltaf3p6