Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53-CRM1 interaction and changing the cellular compartmentalization of p53 protein

Hepatocellular carcinoma (HCC), an aggressive and the fastest growing life-threatening cancer worldwide, is often diagnosed at intermediate or advanced stages of the disease, which substantially limits therapeutic approaches for its successful treatment. This indicates that the prevention of hepatoc...

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Detalles Bibliográficos
Autores principales: Ortega, Juliana F., de Conti, Aline, Tryndyak, Volodymyr, Furtado, Kelly S., Heidor, Renato, Horst, Maria Aderuza, Fernandes, Laura Helena Gasparini, Tavares, Paulo Eduardo Latorre Martins, Pogribna, Marta, Shpyleva, Svitlana, Beland, Frederick A., Pogribny, Igor P., Moreno, Fernando Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029705/
https://www.ncbi.nlm.nih.gov/pubmed/27013579
http://dx.doi.org/10.18632/oncotarget.8248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029705/
https://www.ncbi.nlm.nih.gov/pubmed/27013579
http://dx.doi.org/10.18632/oncotarget.8248

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