Functional characterization and anti-cancer action of the clinical phase II cardiac Na(+)/K(+) ATPase inhibitor istaroxime: in vitro and in vivo properties and cross talk with the membrane androgen receptor

Sodium potassium pump (Na(+)/K(+) ATPase) is a validated pharmacological target for the treatment of various cardiac conditions. Recent published data with Na(+)/K(+) ATPase inhibitors suggest a potent anti-cancer action of these agents in multiple indications. In the present study, we focus on ista...

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Detalles Bibliográficos
Autores principales: Alevizopoulos, Konstantinos, Dimas, Konstantinos, Papadopoulou, Natalia, Schmidt, Eva-Maria, Tsapara, Anna, Alkahtani, Saad, Honisch, Sabina, Prousis, Kyriakos C., Alarifi, Saud, Calogeropoulou, Theodora, Lang, Florian, Stournaras, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029711/
https://www.ncbi.nlm.nih.gov/pubmed/27027435
http://dx.doi.org/10.18632/oncotarget.8329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029711/
https://www.ncbi.nlm.nih.gov/pubmed/27027435
http://dx.doi.org/10.18632/oncotarget.8329

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