BM microenvironmental protection of CML cells from imatinib through Stat5/NF-κB signaling and reversal by Wogonin

Constitutive Stat5 activation enhanced cell survival and resistance to imatinib (IM) in chronic myelogenous leukemia (CML) cells. However, the mechanism of Stat5 activation in mediating resistance to IM in bone marrow (BM) microenvironment has not been evaluated precisely. In this study, we reported...

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Detalles Bibliográficos
Autores principales: Xu, Xuefen, Zhang, Xiaobo, Liu, Yicheng, Yang, Lin, Huang, Shaoliang, Lu, Lu, Wang, Shuhao, Guo, Qinglong, Zhao, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029713/
https://www.ncbi.nlm.nih.gov/pubmed/27027438
http://dx.doi.org/10.18632/oncotarget.8332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029713/
https://www.ncbi.nlm.nih.gov/pubmed/27027438
http://dx.doi.org/10.18632/oncotarget.8332

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