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Netrin-1 suppresses the MEK/ERK pathway and ITGB4 in pancreatic cancer

The axon guidance factor netrin-1 promotes tumorigenesis in multiple types of cancers, particularly at their advanced stages. Here, we investigate whether netrin-1 is involved in the in vivo growth of pancreatic adenocarcinoma. We show that netrin-1 is significantly under-expressed in stage-I/II pan...

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Detalles Bibliográficos
Autores principales: An, Xi-Zhou, Zhao, Zhi-Guo, Luo, Yu-Xuan, Zhang, Ran, Tang, Xiao-Qiang, Hao, De-Long, Zhao, Xiang, Lv, Xiang, Liu, De-Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029736/
https://www.ncbi.nlm.nih.gov/pubmed/27034160
http://dx.doi.org/10.18632/oncotarget.8348