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Predictive value of EGFR overexpression and gene amplification on icotinib efficacy in patients with advanced esophageal squamous cell carcinoma

This study aimed to search for a molecular marker for targeted epithelial growth factor receptor (EGFR) inhibitor Icotinib by analyzing protein expression and amplification of EGFR proto-oncogene in esophageal squamous cell carcinoma (ESCC) patients. Immunohistochemistry and fluorescence in situ hyb...

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Detalles Bibliográficos
Autores principales: Wang, Xi, Niu, Haitao, Fan, Qingxia, Lu, Ping, Ma, Changwu, Liu, Wei, Liu, Ying, Li, Weiwei, Hu, Shaoxuan, Ling, Yun, Guo, Lei, Ying, Jianming, Huang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029738/
https://www.ncbi.nlm.nih.gov/pubmed/27013591
http://dx.doi.org/10.18632/oncotarget.8271