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Successful selection of an infection‐protective anti‐Staphylococcus aureus monoclonal antibody and its protective activity in murine infection models

Recent clinical trials to develop anti‐methicillin‐resistant Staphylococcus aureus (MRSA) therapeutic antibodies have met unsuccessful sequels. To develop more effective antibodies against MRSA infection, a panel of mAbs against S. aureus cell wall was generated and then screened for the most protec...

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Detalles Bibliográficos
Autores principales: Ohsawa, Hiroyoshi, Baba, Tadashi, Enami, Jumpei, Hiramatsu, Keiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029779/
https://www.ncbi.nlm.nih.gov/pubmed/25659598
http://dx.doi.org/10.1111/1348-0421.12242