Cargando…

Successful selection of an infection‐protective anti‐Staphylococcus aureus monoclonal antibody and its protective activity in murine infection models

Recent clinical trials to develop anti‐methicillin‐resistant Staphylococcus aureus (MRSA) therapeutic antibodies have met unsuccessful sequels. To develop more effective antibodies against MRSA infection, a panel of mAbs against S. aureus cell wall was generated and then screened for the most protec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ohsawa, Hiroyoshi, Baba, Tadashi, Enami, Jumpei, Hiramatsu, Keiichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029779/ https://www.ncbi.nlm.nih.gov/pubmed/25659598 http://dx.doi.org/10.1111/1348-0421.12242

Ejemplares similares

Monoclonal antibody anti-PBP2a protects mice against MRSA (methicillin-resistant Staphylococcus aureus) infections
por: Saraiva, Felipe Betoni, et al.
Publicado: (2019)

Induction of protective interferon-β responses in murine osteoblasts following Staphylococcus aureus infection
por: Johnson, M. Brittany, et al.
Publicado: (2022)

A natural human monoclonal antibody targeting Staphylococcus Protein A protects against Staphylococcus aureus bacteremia
por: Varshney, Avanish K., et al.
Publicado: (2018)

Monoclonal Antibody Targeting Staphylococcus aureus Surface Protein A (SasA) Protect Against Staphylococcus aureus Sepsis and Peritonitis in Mice
por: Yang, Yilong, et al.
Publicado: (2016)

Identification of a Human Anti-Alpha-Toxin Monoclonal Antibody Against Staphylococcus aureus Infection
por: Liu, Fangjie, et al.
Publicado: (2021)

Genomic Basis for Methicillin Resistance in Staphylococcus aureus
por: Hiramatsu, Keiichi, et al.
Publicado: (2013)

CID12261165, a flavonoid compound as antibacterial agents against quinolone-resistant Staphylococcus aureus
por: Morimoto, Yuh, et al.
Publicado: (2023)

Antibiotic Combined with Epitope-Specific Monoclonal Antibody Cocktail Protects Mice Against Bacteremia and Acute Pneumonia from Methicillin-Resistant Staphylococcus aureus Infection
por: Duan, LianLi, et al.
Publicado: (2021)

Commensal Staphylococcus aureus Provokes Immunity to Protect against Skin Infection of Methicillin-Resistant Staphylococcus aureus
por: Yang, John-Jackson, et al.
Publicado: (2018)

Staphylococcus aureus Membrane-Derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models
por: Askarian, Fatemeh, et al.
Publicado: (2018)

Transient Monoclonal Gammopathy Induced by Disseminated Staphylococcus aureus Infection
por: Stoimenis, Dimitrios, et al.
Publicado: (2012)

Protective Efficacy and Mechanism of Passive Immunization with Polyclonal Antibodies in a Sepsis Model of Staphylococcus aureus Infection
por: Zhang, Jinyong, et al.
Publicado: (2015)

Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection
por: Brown, Aisling F., et al.
Publicado: (2015)

Protective Role of Surfactant Protein D in Ocular Staphylococcus aureus Infection
por: Zhang, Zhiyong, et al.
Publicado: (2015)

T Cell Immunity and the Quest for Protective Vaccines against Staphylococcus aureus Infection
por: Armentrout, Erin I., et al.
Publicado: (2020)

Tissue specificity drives protective immunity against Staphylococcus aureus infection
por: Beesetty, Pavani, et al.
Publicado: (2022)

Commentary: Staphylococcus aureus Membrane-Derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models
por: Heilbronner, Simon
Publicado: (2018)

Anti-TRAP/SSP2 monoclonal antibodies can inhibit sporozoite infection and may enhance protection of anti-CSP monoclonal antibodies
por: Wilder, Brandon K., et al.
Publicado: (2022)

Regional outbreak of community-associated methicillin-resistant Staphylococcus aureus ST834 in Japanese children
por: Uehara, Yuki, et al.
Publicado: (2019)

Protection against Staphylococcus aureus Colonization and Infection by B- and T-Cell-Mediated Mechanisms
por: Zhang, Fan, et al.
Publicado: (2018)

Murine models of orthopedic infection featuring Staphylococcus aureus biofilm
por: Dao, Aiken, et al.
Publicado: (2023)

Protecting intubated patients from the threat of antimicrobial resistant infections with monoclonal antibodies
por: Baker, Stephen, et al.
Publicado: (2020)

The Staphylococcus aureus Peptidoglycan Protects Mice against the Pathogen and Eradicates Experimentally Induced Infection
por: Capparelli, Rosanna, et al.
Publicado: (2011)

Orthosiphon stamineus protects Caenorhabditis elegans against Staphylococcus aureus infection through immunomodulation
por: Kong, Cin, et al.
Publicado: (2014)

Preconditioning with Lipopolysaccharide or Lipoteichoic Acid Protects against Staphylococcus aureus Mammary Infection in Mice
por: Breyne, Koen, et al.
Publicado: (2017)

Adenosine synthase A contributes to recurrent Staphylococcus aureus infection by dampening protective immunity
por: Deng, Jian, et al.
Publicado: (2021)

The protective effect of URP20 on ocular Staphylococcus aureus and Escherichia coli infection in rats
por: Li, Meng, et al.
Publicado: (2022)

Staphylococcus aureus Host Tropism and Its Implications for Murine Infection Models
por: Mrochen, Daniel M., et al.
Publicado: (2020)

Vaccine protection against Staphylococcus aureus pneumonia
por: Wardenburg, Juliane Bubeck, et al.
Publicado: (2008)

MAE4, an eLtaS monoclonal antibody, blocks Staphylococcus aureus virulence
por: Liu, Yu, et al.
Publicado: (2015)

Catching the evader: Can monoclonal antibodies interfere with Staphylococcus aureus immune escape?
por: Rasigade, Jean-Philippe
Publicado: (2017)

Anti-IL-20 monoclonal antibody inhibited inflammation and protected against cartilage destruction in murine models of osteoarthritis
por: Hsu, Yu-Hsiang, et al.
Publicado: (2017)

Characterization of the mechanism of protection mediated by CS-D7, a monoclonal antibody to Staphylococcus aureus iron regulated surface determinant B (IsdB)
por: Pancari, Gregory, et al.
Publicado: (2012)

Vancomycin Heteroresistance in Methicillin-resistant Staphylococcus aureus, Taiwan
por: Wang, Jiun-Ling, et al.
Publicado: (2004)

Staphylococcus aureus Infection Induced Oxidative Imbalance in Neutrophils: Possible Protective Role of Nanoconjugated Vancomycin
por: Chakraborty, Subhankari Prasad, et al.
Publicado: (2012)

Estradiol ameliorates arthritis and protects against systemic bone loss in Staphylococcus aureus infection in mice
por: Gjertsson, Inger, et al.
Publicado: (2012)

Evaluation of Genetically Inactivated Alpha Toxin for Protection in Multiple Mouse Models of Staphylococcus aureus Infection
por: Brady, Rebecca A., et al.
Publicado: (2013)

Acacetin Protects Mice from Staphylococcus aureus Bloodstream Infection by Inhibiting the Activity of Sortase A
por: Bi, Chongwei, et al.
Publicado: (2016)

Quercetin protects rats from catheter‐related Staphylococcus aureus infections by inhibiting coagulase activity
por: Wang, Lin, et al.
Publicado: (2019)

Myricetin protects Galleria mellonella against Staphylococcus aureus infection and inhibits multiple virulence factors
por: Silva, L. N., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ehbgnnfaaab08ikm9lp4r88cda