Cargando…

Signaling Modification by GPCR Heteromer and Its Implication on X-Linked Nephrogenic Diabetes Insipidus

The involvement of secretin (SCT) and secretin receptor (SCTR) in regulating body water homeostasis is well established. Identified as one of the vasopressin (Vp)-independent mechanisms in fluid balance, SCT regulates aquaporin 2 (AQP2) in the kidney distal collecting duct cells through activating i...

Descripción completa

Detalles Bibliográficos
Autores principales: Ng, Hans K. H., Harikumar, Kaleeckal G., Miller, Laurence J., Chow, Billy K. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029868/
https://www.ncbi.nlm.nih.gov/pubmed/27649563
http://dx.doi.org/10.1371/journal.pone.0163086