Single Nucleotide Polymorphisms in Cellular Drug Transporters Are Associated with Intolerance to Antiretroviral Therapy in Brazilian HIV-1 Positive Individuals

Adverse reactions are the main cause of treatment discontinuation among HIV+ individuals. Genes related to drug absorption, distribution, metabolism and excretion (ADME) influence drug bioavailability and treatment response. We have investigated the association between single nucleotide polymorphism...

Descripción completa

Detalles Bibliográficos
Autores principales: Arruda, Mônica Barcellos, Campagnari, Francine, de Almeida, Tailah Bernardo, Couto-Fernandez, José Carlos, Tanuri, Amilcar, Cardoso, Cynthia Chester
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029869/
https://www.ncbi.nlm.nih.gov/pubmed/27648838
http://dx.doi.org/10.1371/journal.pone.0163170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029869/
https://www.ncbi.nlm.nih.gov/pubmed/27648838
http://dx.doi.org/10.1371/journal.pone.0163170

Ejemplares similares