Single Nucleotide Polymorphisms in Cellular Drug Transporters Are Associated with Intolerance to Antiretroviral Therapy in Brazilian HIV-1 Positive Individuals

Adverse reactions are the main cause of treatment discontinuation among HIV+ individuals. Genes related to drug absorption, distribution, metabolism and excretion (ADME) influence drug bioavailability and treatment response. We have investigated the association between single nucleotide polymorphism...

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Detalles Bibliográficos
Autores principales: Arruda, Mônica Barcellos, Campagnari, Francine, de Almeida, Tailah Bernardo, Couto-Fernandez, José Carlos, Tanuri, Amilcar, Cardoso, Cynthia Chester
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029869/
https://www.ncbi.nlm.nih.gov/pubmed/27648838
http://dx.doi.org/10.1371/journal.pone.0163170

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