Increased taurine in pre-weaned juvenile mdx mice greatly reduces the acute onset of myofibre necrosis and dystropathology and prevents inflammation

Background: The mdx mouse model for the fatal muscle wasting disease Duchenne Muscular Dystrophy (DMD) shows a very mild pathology once growth has ceased, with low levels of myofibre necrosis in adults. However, from about 3 weeks of post-natal age, muscles of juvenile mdx mice undergo an acute bout...

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Detalles Bibliográficos
Autores principales: Terrill, Jessica R., Grounds, Miranda D, Arthur, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Muscular Dystrophy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029885/
https://www.ncbi.nlm.nih.gov/pubmed/27679740
http://dx.doi.org/10.1371/currents.md.77be6ec30e8caf19529a00417614a072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029885/
https://www.ncbi.nlm.nih.gov/pubmed/27679740
http://dx.doi.org/10.1371/currents.md.77be6ec30e8caf19529a00417614a072

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