The gp63 Gene Cluster Is Highly Polymorphic in Natural Leishmania (Viannia) braziliensis Populations, but Functional Sites Are Conserved

GP63 or leishmanolysin is the major surface protease of Leishmania spp. involved in parasite virulence and host cell interaction. As such, GP63 is a potential target of eventual vaccines against these protozoa. In the current study we evaluate the polymorphism of gp63 in Leishmania (Viannia) brazili...

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Detalles Bibliográficos
Autores principales: Medina, Lilian S., Souza, Bruno Araújo, Queiroz, Adriano, Guimarães, Luiz Henrique, Lima Machado, Paulo Roberto, M Carvalho, Edgar, Wilson, Mary Edythe, Schriefer, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029894/
https://www.ncbi.nlm.nih.gov/pubmed/27648939
http://dx.doi.org/10.1371/journal.pone.0163284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029894/
https://www.ncbi.nlm.nih.gov/pubmed/27648939
http://dx.doi.org/10.1371/journal.pone.0163284

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