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HIV-1 Vpr Abrogates the Effect of TSG101 Overexpression to Support Virus Release

HIV-1 budding requires interaction between Gag and cellular TSG101 to initiate viral particle assembly and release via the endosomal sorting complexes required for transport (ESCRT) pathway. However, some reports show that overexpression of TSG101 inhibits virus release by disruption of Gag targetin...

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Detalles Bibliográficos
Autores principales: Chutiwitoonchai, Nopporn, Siarot, Lowela, Takeda, Eri, Shioda, Tatsuo, Ueda, Motoki, Aida, Yoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029901/
https://www.ncbi.nlm.nih.gov/pubmed/27648839
http://dx.doi.org/10.1371/journal.pone.0163100