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Assessment of Carbon Dioxide, Carbon Dioxide/Oxygen, Isoflurane and Pentobarbital Killing Methods in Adult Female Sprague-Dawley Rats
BACKGROUND: Exposure to carbon dioxide (CO(2)) gas as a killing method is aversive and exposure to high concentrations is likely to be painful. Bradycardia during exposure to CO(2) is associated with nociception and pain. However, it is unclear if bradycardia occurs before loss of consciousness as d...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029904/ https://www.ncbi.nlm.nih.gov/pubmed/27648836 http://dx.doi.org/10.1371/journal.pone.0162639 |