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The Inhibitory Effects of Anti-Oxidants on Ultraviolet-Induced Up-Regulation of the Wrinkling-Inducing Enzyme Neutral Endopeptidase in Human Fibroblasts

We recently reported that the over-expression of skin fibroblast-derived neutral endopeptidase (NEP) plays a pivotal role in impairing the three-dimensional architecture of dermal elastic fibers during the biological mechanism of ultraviolet (UV)-induced skin wrinkling. In that process, a UVB-associ...

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Detalles Bibliográficos
Autores principales: Nakajima, Hiroaki, Terazawa, Shuko, Niwano, Takao, Yamamoto, Yorihiro, Imokawa, Genji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029912/
https://www.ncbi.nlm.nih.gov/pubmed/27648570
http://dx.doi.org/10.1371/journal.pone.0161580