Deletion of mTORC1 Activity in CD4+ T Cells Is Associated with Lung Fibrosis and Increased γδ T Cells

Pulmonary fibrosis is a devastating, incurable disease in which chronic inflammation and dysregulated, excessive wound healing lead to progressive fibrosis, lung dysfunction, and ultimately death. Prior studies have implicated the cytokine IL-17A and Th17 cells in promoting the development of fibros...

Descripción completa

Detalles Bibliográficos
Autores principales: Vigeland, Christine L., Collins, Samuel L., Chan-Li, Yee, Hughes, Andrew H., Oh, Min-Hee, Powell, Jonathan D., Horton, Maureen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029914/
https://www.ncbi.nlm.nih.gov/pubmed/27649073
http://dx.doi.org/10.1371/journal.pone.0163288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029914/
https://www.ncbi.nlm.nih.gov/pubmed/27649073
http://dx.doi.org/10.1371/journal.pone.0163288

Ejemplares similares