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Deletion of mTORC1 Activity in CD4+ T Cells Is Associated with Lung Fibrosis and Increased γδ T Cells
Pulmonary fibrosis is a devastating, incurable disease in which chronic inflammation and dysregulated, excessive wound healing lead to progressive fibrosis, lung dysfunction, and ultimately death. Prior studies have implicated the cytokine IL-17A and Th17 cells in promoting the development of fibros...
Autores principales: | Vigeland, Christine L., Collins, Samuel L., Chan-Li, Yee, Hughes, Andrew H., Oh, Min-Hee, Powell, Jonathan D., Horton, Maureen R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029914/ https://www.ncbi.nlm.nih.gov/pubmed/27649073 http://dx.doi.org/10.1371/journal.pone.0163288 |
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