Inflammatory Adipokines Decrease Expression of Two High Molecular Weight Isoforms of Tropomyosin Similar to the Change in Type 2 Diabetic Patients

Cardiovascular disease and cancer are increased in Type 2 diabetes. TPM1 and TPM4 genes encode proteins associated with cardiovascular and neoplastic disease. High (HMW) and low (LMW) molecular weight isoforms from TPM1 and TPM4 are altered in several cancer cells and the 3'UTR of TPM1 mRNA is...

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Detalles Bibliográficos
Autores principales: Savill, Stuart A., Leitch, Helen F., Harvey, John N., Thomas, Trevor H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029944/
https://www.ncbi.nlm.nih.gov/pubmed/27649540
http://dx.doi.org/10.1371/journal.pone.0162908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029944/
https://www.ncbi.nlm.nih.gov/pubmed/27649540
http://dx.doi.org/10.1371/journal.pone.0162908

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