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Bmi-1 promotes the invasion and migration of colon cancer stem cells through the downregulation of E-cadherin

Metastasis and recurrence are the challenges of cancer therapy. Recently, mounting evidence has suggested that cancer stem cells (CSCs) and epithelial-mesenchymal transition (EMT) are critical factors in tumor metastasis and recurrence. The oncogene, Bmi-1, promotes the development of hematologic ma...

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Detalles Bibliográficos
Autores principales: Zhang, Zefeng, Bu, Xiaoling, Chen, Hao, Wang, Qiyi, Sha, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029956/
https://www.ncbi.nlm.nih.gov/pubmed/27600678
http://dx.doi.org/10.3892/ijmm.2016.2730