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Bmi-1 promotes the invasion and migration of colon cancer stem cells through the downregulation of E-cadherin
Metastasis and recurrence are the challenges of cancer therapy. Recently, mounting evidence has suggested that cancer stem cells (CSCs) and epithelial-mesenchymal transition (EMT) are critical factors in tumor metastasis and recurrence. The oncogene, Bmi-1, promotes the development of hematologic ma...
Autores principales: | Zhang, Zefeng, Bu, Xiaoling, Chen, Hao, Wang, Qiyi, Sha, Weihong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029956/ https://www.ncbi.nlm.nih.gov/pubmed/27600678 http://dx.doi.org/10.3892/ijmm.2016.2730 |
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