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Mechanism for nuclease regulation in RecBCD

In bacterial cells, processing of double-stranded DNA breaks for repair by homologous recombination is catalysed by AddAB, AdnAB or RecBCD-type helicase-nucleases. These enzyme complexes are highly processive, duplex unwinding and degrading machines that require tight regulation. Here, we report the...

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Detalles Bibliográficos
Autores principales: Wilkinson, Martin, Chaban, Yuriy, Wigley, Dale B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030088/
https://www.ncbi.nlm.nih.gov/pubmed/27644322
http://dx.doi.org/10.7554/eLife.18227