Muscle contraction is required to maintain the pool of muscle progenitors via YAP and NOTCH during fetal myogenesis

The importance of mechanical activity in the regulation of muscle progenitors during chick development has not been investigated. We show that immobilization decreases NOTCH activity and mimics a NOTCH loss-of-function phenotype, a reduction in the number of muscle progenitors and increased differen...

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Detalles Bibliográficos
Autores principales: Esteves de Lima, Joana, Bonnin, Marie-Ange, Birchmeier, Carmen, Duprez, Delphine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030091/
https://www.ncbi.nlm.nih.gov/pubmed/27554485
http://dx.doi.org/10.7554/eLife.15593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030091/
https://www.ncbi.nlm.nih.gov/pubmed/27554485
http://dx.doi.org/10.7554/eLife.15593

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