Follicular helper T cells progressively differentiate to regulate the germinal center response

Germinal center (GC) B cells undergo affinity selection, dependent upon interactions with CD4(+) follicular helper T (T(FH)) cells. We demonstrate that T(FH) cells progressed through transcriptionally and functionally distinct stages, providing differential signals for GC regulation. They initially...

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Detalles Bibliográficos
Autores principales: Weinstein, Jason S., Herman, Edward I., Lainez, Begoña, Licona-Limón, Paula, Esplugues, Enric, Flavell, Richard, Craft, Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030190/
https://www.ncbi.nlm.nih.gov/pubmed/27573866
http://dx.doi.org/10.1038/ni.3554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030190/
https://www.ncbi.nlm.nih.gov/pubmed/27573866
http://dx.doi.org/10.1038/ni.3554

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