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VEGFR-2 reduces while combined VEGFR-2 and -3 signaling increases inflammation in apical periodontitis

BACKGROUND: In apical periodontitis, oral pathogens provoke an inflammatory response in the apical area that induces bone resorptive lesions. In inflammation, angio- and lymphangiogenesis take place. Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) are key players in these pr...

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Detalles Bibliográficos
Autores principales: Virtej, Anca, Papadakou, Panagiota, Sasaki, Hajime, Bletsa, Athanasia, Berggreen, Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030260/
https://www.ncbi.nlm.nih.gov/pubmed/27650043
http://dx.doi.org/10.3402/jom.v8.32433