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Differential Regulation of Self-reactive CD4(+) T Cells in Cervical Lymph Nodes and Central Nervous System during Viral Encephalomyelitis

Viral infections have long been implicated as triggers of autoimmune diseases, including multiple sclerosis (MS), a central nervous system (CNS) inflammatory demyelinating disorder. Epitope spreading, molecular mimicry, cryptic antigen, and bystander activation have been implicated as mechanisms res...

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Detalles Bibliográficos
Autores principales: Savarin, Carine, Bergmann, Cornelia C., Hinton, David R., Stohlman, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030268/
https://www.ncbi.nlm.nih.gov/pubmed/27708643
http://dx.doi.org/10.3389/fimmu.2016.00370