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Comparison of artesunate–mefloquine and artemether–lumefantrine fixed-dose combinations for treatment of uncomplicated Plasmodium falciparum malaria in children younger than 5 years in sub-Saharan Africa: a randomised, multicentre, phase 4 trial

BACKGROUND: WHO recommends combinations of an artemisinin derivative plus an antimalarial drug of longer half-life as treatment options for uncomplicated Plasmodium falciparum infection. In Africa, artemether–lumefantrine is the most widely used artemisinin-based combination therapy, whereas artesun...

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Detalles Bibliográficos
Autores principales: Sirima, Sodiomon B, Ogutu, Bernhards, Lusingu, John P A, Mtoro, Ali, Mrango, Zakayo, Ouedraogo, Alphonse, Yaro, Jean Baptiste, Onyango, Kevin Omondi, Gesase, Samwel, Mnkande, Ernest, Ngocho, James Samwel, Ackermann, Isabelle, Aubin, François, Vanraes, Joelle, Strub, Nathalie, Carn, Gwenaelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science ;, The Lancet Pub. Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030279/
https://www.ncbi.nlm.nih.gov/pubmed/27430374
http://dx.doi.org/10.1016/S1473-3099(16)30020-2