Cargando…

Comparison of artesunate–mefloquine and artemether–lumefantrine fixed-dose combinations for treatment of uncomplicated Plasmodium falciparum malaria in children younger than 5 years in sub-Saharan Africa: a randomised, multicentre, phase 4 trial

BACKGROUND: WHO recommends combinations of an artemisinin derivative plus an antimalarial drug of longer half-life as treatment options for uncomplicated Plasmodium falciparum infection. In Africa, artemether–lumefantrine is the most widely used artemisinin-based combination therapy, whereas artesun...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sirima, Sodiomon B, Ogutu, Bernhards, Lusingu, John P A, Mtoro, Ali, Mrango, Zakayo, Ouedraogo, Alphonse, Yaro, Jean Baptiste, Onyango, Kevin Omondi, Gesase, Samwel, Mnkande, Ernest, Ngocho, James Samwel, Ackermann, Isabelle, Aubin, François, Vanraes, Joelle, Strub, Nathalie, Carn, Gwenaelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science ;, The Lancet Pub. Group 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030279/ https://www.ncbi.nlm.nih.gov/pubmed/27430374 http://dx.doi.org/10.1016/S1473-3099(16)30020-2

Ejemplares similares

A randomized, open-label, comparative efficacy trial of artemether-lumefantrine suspension versus artemether-lumefantrine tablets for treatment of uncomplicated Plasmodium falciparum malaria in children in western Kenya
por: Juma, Elizabeth A, et al.
Publicado: (2008)

Population pharmacokinetics of mefloquine, piperaquine and artemether-lumefantrine in Cambodian and Tanzanian malaria patients
por: Staehli Hodel, Eva Maria, et al.
Publicado: (2013)

Quinine plus clindamycin vs artemether-lumefantrine for treatment of uncomplicated falciparum malaria in western Kenya
por: Obonyo, Charles O., et al.
Publicado: (2022)

Development of a pediatric formulation for treatment of P. falciparum malaria: Coartem(®) (artemether-lumefantrine) Dispersible
por: Bassat, Quique, et al.
Publicado: (2014)

Treatment of asymptomatic carriers with artemether-lumefantrine: an opportunity to reduce the burden of malaria?
por: Ogutu, Bernhards, et al.
Publicado: (2010)

Efficacy and Tolerability Outcomes of a Phase II, Randomized, Open-Label, Multicenter Study of a New Water-Dispersible Pediatric Formulation of Dihydroartemisinin-Piperaquine for the Treatment of Uncomplicated Plasmodium falciparum Malaria in African Infants
por: Gargano, Nicola, et al.
Publicado: (2017)

A randomized controlled trial of dihydroartemisinin-piperaquine, artesunate-mefloquine and extended artemether-lumefantrine treatments for malaria in pregnancy on the Thailand-Myanmar border
por: Saito, Makoto, et al.
Publicado: (2021)

A randomized trial of artemether-lumefantrine versus mefloquine-artesunate for the treatment of uncomplicated multi-drug resistant Plasmodium falciparum on the western border of Thailand
por: Hutagalung, Robert, et al.
Publicado: (2005)

Population pharmacokinetics and pharmacodynamics of the artesunate–mefloquine fixed dose combination for the treatment of uncomplicated falciparum malaria in African children
por: Guidi, Monia, et al.
Publicado: (2019)

Increased systemic exposures of artemether and dihydroartemisinin in infants under 5 kg with uncomplicated Plasmodium falciparum malaria treated with artemether-lumefantrine (Coartem®)
por: Tiono, Alfred B, et al.
Publicado: (2015)

The content of African diets is adequate to achieve optimal efficacy with fixed-dose artemether-lumefantrine: a review of the evidence
por: Premji, Zulfiqarali G, et al.
Publicado: (2008)

Synergism in Antiplasmodial Activities of Artemether and Lumefantrine in Combination with Securidaca longipedunculata Fresen (Polygalaceae)
por: Ochora, Douglas O., et al.
Publicado: (2021)

Drug Interactions between Dolutegravir and Artemether-Lumefantrine or Artesunate-Amodiaquine
por: Walimbwa, Stephen I., et al.
Publicado: (2019)

Malaria Transmission Dynamics in a High-Transmission Setting of Western Kenya and the Inadequate Treatment Response to Artemether-Lumefantrine in an Asymptomatic Population
por: Andagalu, Ben, et al.
Publicado: (2022)

Longitudinal study on Plasmodium falciparum gametocyte carriage following artemether-lumefantrine administration in a cohort of children aged 12–47 months living in Western Kenya, a high transmission area
por: Andagalu, Ben, et al.
Publicado: (2014)

Efficacy and safety of artemether-lumefantrine and dihydroartemisinin-piperaquine in the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children aged less than five years: results of an open-label, randomized, single-centre study
por: Ogutu, Bernhards R, et al.
Publicado: (2014)

Development of a dissolution method for lumefantrine and artemether in immediate release fixed dose artemether/lumefantrine tablets
por: Belew, Sileshi, et al.
Publicado: (2020)

The clinical efficacy of artemether/lumefantrine (Coartem(®))
por: Makanga, Michael, et al.
Publicado: (2009)

Efficacy of 3-day low dose quinine plus clindamycin versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children (CLINDAQUINE): an open-label randomized trial
por: Obonyo, Charles O., et al.
Publicado: (2022)

Plasmodium falciparum gametocyte dynamics after pyronaridine–artesunate or artemether–lumefantrine treatment
por: Roth, Johanna M., et al.
Publicado: (2018)

Community screening and treatment of asymptomatic carriers of Plasmodium falciparum with artemether-lumefantrine to reduce malaria disease burden: a modelling and simulation analysis
por: Kern, Steven E, et al.
Publicado: (2011)

Pharmacokinetics of artemether and dihydroartemisinin in healthy Pakistani male volunteers treated with artemether-lumefantrine
por: Ali, Shabana, et al.
Publicado: (2010)

Comparison of azithromycin plus chloroquine versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in children in Africa: a randomized, open-label study
por: Chandra, Richa, et al.
Publicado: (2015)

Electrocardiographic study in Ghanaian children with uncomplicated malaria, treated with artesunate-amodiaquine or artemether-lumefantrine
por: Adjei, George O, et al.
Publicado: (2012)

Efficacy of artesunate-amodiaquine and artemether-lumefantrine for uncomplicated Plasmodium falciparum malaria in Madagascar, 2018
por: Dentinger, Catherine M., et al.
Publicado: (2021)

Temporal trends in prevalence of Plasmodium falciparum molecular markers selected for by artemether–lumefantrine treatment in pre-ACT and post-ACT parasites in western Kenya
por: Achieng, Angela O., et al.
Publicado: (2015)

Similar efficacy and safety of artemether-lumefantrine (Coartem(®)) in African infants and children with uncomplicated falciparum malaria across different body weight ranges
por: Bassat, Quique, et al.
Publicado: (2011)

Quality Assessment of Artemether-Lumefantrine Samples and Artemether Injections Sold in the Cape Coast Metropolis
por: Prah, James, et al.
Publicado: (2016)

Artemether–lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria
por: Ehrhardt, Stephan, et al.
Publicado: (2009)

Continued Low Efficacy of Artemether-Lumefantrine in Angola in 2019
por: Dimbu, Pedro Rafael, et al.
Publicado: (2021)

In vivo efficacy of artemether-lumefantrine and artesunate-amodiaquine for uncomplicated Plasmodium falciparum malaria in Malawi, 2014
por: Paczkowski, Magdalena, et al.
Publicado: (2016)

An Open Label, Randomised Trial of Artesunate+Amodiaquine, Artesunate+Chlorproguanil-Dapsone and Artemether-Lumefantrine for the Treatment of Uncomplicated Malaria
por: Owusu-Agyei, Seth, et al.
Publicado: (2008)

Population Pharmacokinetics and Pharmacodynamics of Lumefantrine in Young Ugandan Children Treated With Artemether-Lumefantrine for Uncomplicated Malaria
por: Tchaparian, Eskouhie, et al.
Publicado: (2016)

Risks of Hemolysis in Glucose-6-Phosphate Dehydrogenase Deficient Infants Exposed to Chlorproguanil-Dapsone, Mefloquine and Sulfadoxine-Pyrimethamine as Part of Intermittent Presumptive Treatment of Malaria in Infants
por: Poirot, Eugenie, et al.
Publicado: (2015)

High efficacy of artemether–lumefantrine and dihydroartemisinin–piperaquine for the treatment of uncomplicated falciparum malaria in Muheza and Kigoma Districts, Tanzania
por: Mandara, Celine I., et al.
Publicado: (2018)

Therapeutic efficacy and safety of artesunate + amodiaquine and artemether + lumefantrine in treating uncomplicated Plasmodium falciparum malaria in children on the rainy south-east coast of Madagascar
por: Irinantenaina, Judickaëlle, et al.
Publicado: (2023)

The Use of Artemether-Lumefantrine for the Treatment of Uncomplicated Plasmodium vivax Malaria
por: Bassat, Quique
Publicado: (2011)

Therapeutic efficacy of artemether-lumefantrine in uncomplicated falciparum malaria in India
por: Valecha, Neena, et al.
Publicado: (2009)

Artemether/Lumefantrine for the Treatment of P. malariae in a Patient on Hemodialysis
por: Patrocínio-Jesus, Rita, et al.
Publicado: (2019)

Monitoring of the Sensitivity In Vivo of Plasmodium falciparum to Artemether-Lumefantrine in Mali
por: Diarra, Modibo, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_gjgc1dotif3g8l8dmtc4osfh7g