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The Effects of Signal Erosion and Core Genome Reduction on the Identification of Diagnostic Markers

Whole-genome sequence (WGS) data are commonly used to design diagnostic targets for the identification of bacterial pathogens. To do this effectively, genomics databases must be comprehensive to identify the strict core genome that is specific to the target pathogen. As additional genomes are analyz...

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Detalles Bibliográficos
Autores principales: Sahl, Jason W., Vazquez, Adam J., Hall, Carina M., Busch, Joseph D., Tuanyok, Apichai, Mayo, Mark, Schupp, James M., Lummis, Madeline, Pearson, Talima, Shippy, Kenzie, Colman, Rebecca E., Allender, Christopher J., Theobald, Vanessa, Sarovich, Derek S., Price, Erin P., Hutcheson, Alex, Korlach, Jonas, LiPuma, John J., Ladner, Jason, Lovett, Sean, Koroleva, Galina, Palacios, Gustavo, Limmathurotsakul, Direk, Wuthiekanun, Vanaporn, Wongsuwan, Gumphol, Currie, Bart J., Keim, Paul, Wagner, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030356/
https://www.ncbi.nlm.nih.gov/pubmed/27651357
http://dx.doi.org/10.1128/mBio.00846-16