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The Effects of Signal Erosion and Core Genome Reduction on the Identification of Diagnostic Markers
Whole-genome sequence (WGS) data are commonly used to design diagnostic targets for the identification of bacterial pathogens. To do this effectively, genomics databases must be comprehensive to identify the strict core genome that is specific to the target pathogen. As additional genomes are analyz...
Autores principales: | Sahl, Jason W., Vazquez, Adam J., Hall, Carina M., Busch, Joseph D., Tuanyok, Apichai, Mayo, Mark, Schupp, James M., Lummis, Madeline, Pearson, Talima, Shippy, Kenzie, Colman, Rebecca E., Allender, Christopher J., Theobald, Vanessa, Sarovich, Derek S., Price, Erin P., Hutcheson, Alex, Korlach, Jonas, LiPuma, John J., Ladner, Jason, Lovett, Sean, Koroleva, Galina, Palacios, Gustavo, Limmathurotsakul, Direk, Wuthiekanun, Vanaporn, Wongsuwan, Gumphol, Currie, Bart J., Keim, Paul, Wagner, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030356/ https://www.ncbi.nlm.nih.gov/pubmed/27651357 http://dx.doi.org/10.1128/mBio.00846-16 |
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