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Cathelicidin Antimicrobial Peptides with Reduced Activation of Toll-Like Receptor Signaling Have Potent Bactericidal Activity against Colistin-Resistant Bacteria

The world is at the precipice of a postantibiotic era in which medical procedures and minor injuries can result in bacterial infections that are no longer effectively treated by antibiotics. Cathelicidins are peptides produced by animals to combat bacterial infections and to regulate innate immune r...

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Detalles Bibliográficos
Autores principales: Kao, Cheng, Lin, Xiaoyan, Yi, Guanghui, Zhang, Yunliang, Rowe-Magnus, Dean A., Bush, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030359/
https://www.ncbi.nlm.nih.gov/pubmed/27651360
http://dx.doi.org/10.1128/mBio.01418-16