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Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype

The outcome of Mycobacterium tuberculosis infection and the immunological response to the bacillus Calmette-Guerin (BCG) vaccine are highly variable in humans. Deciphering the relative importance of host genetics, environment, and vaccine preparation for the efficacy of BCG has proven difficult in n...

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Detalles Bibliográficos
Autores principales: Smith, Clare M., Proulx, Megan K., Olive, Andrew J., Laddy, Dominick, Mishra, Bibhuti B., Moss, Caitlin, Gutierrez, Nuria Martinez, Bellerose, Michelle M., Barreira-Silva, Palmira, Phuah, Jia Yao, Baker, Richard E., Behar, Samuel M., Kornfeld, Hardy, Evans, Thomas G., Beamer, Gillian, Sassetti, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030360/
https://www.ncbi.nlm.nih.gov/pubmed/27651361
http://dx.doi.org/10.1128/mBio.01516-16