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Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype
The outcome of Mycobacterium tuberculosis infection and the immunological response to the bacillus Calmette-Guerin (BCG) vaccine are highly variable in humans. Deciphering the relative importance of host genetics, environment, and vaccine preparation for the efficacy of BCG has proven difficult in n...
Autores principales: | Smith, Clare M., Proulx, Megan K., Olive, Andrew J., Laddy, Dominick, Mishra, Bibhuti B., Moss, Caitlin, Gutierrez, Nuria Martinez, Bellerose, Michelle M., Barreira-Silva, Palmira, Phuah, Jia Yao, Baker, Richard E., Behar, Samuel M., Kornfeld, Hardy, Evans, Thomas G., Beamer, Gillian, Sassetti, Christopher M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030360/ https://www.ncbi.nlm.nih.gov/pubmed/27651361 http://dx.doi.org/10.1128/mBio.01516-16 |
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