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Prediction and In Silico Identification of Novel B-Cells and T-Cells Epitopes in the S1-Spike Glycoprotein of M41 and CR88 (793/B) Infectious Bronchitis Virus Serotypes for Application in Peptide Vaccines

Bioinformatic analysis was used to predict antigenic B-cell and T-cell epitopes within the S1 glycoprotein of M41 and CR88 IBV strains. A conserved linear B-cell epitope peptide, YTSNETTDVTS(175–185), was identified in M41 IBV strains while three such epitopes types namely, VSNASPNSGGVD(279–290), HP...

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Detalles Bibliográficos
Autores principales: Bande, Faruku, Arshad, Siti Suri, Hair Bejo, Mohd, Kadkhodaei, Saeid, Omar, Abdul Rahman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030393/
https://www.ncbi.nlm.nih.gov/pubmed/27667997
http://dx.doi.org/10.1155/2016/5484972