Engineering new balancer chromosomes in C. elegans via CRISPR/Cas9

Balancer chromosomes are convenient tools used to maintain lethal mutations in heterozygotes. We established a method for engineering new balancers in C. elegans by using the CRISPR/Cas9 system in a non-homologous end-joining mutant. Our studies will make it easier for researchers to maintain lethal...

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Detalles Bibliográficos
Autores principales: Iwata, Satoru, Yoshina, Sawako, Suehiro, Yuji, Hori, Sayaka, Mitani, Shohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030659/
https://www.ncbi.nlm.nih.gov/pubmed/27650892
http://dx.doi.org/10.1038/srep33840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030659/
https://www.ncbi.nlm.nih.gov/pubmed/27650892
http://dx.doi.org/10.1038/srep33840

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