Mechanistic insight into the norepinephrine-induced fibrosis in systemic sclerosis

Raynaud’s phenomenon is frequently observed in systemic sclerosis (SSc) patients, and cold- or stress-induced norepinephrine (NE) has been speculated to be associated with vasoconstriction. Objective was to elucidate the role of NE in fibrosis in SSc. IL-6 is a potent stimulator of collagen producti...

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Detalles Bibliográficos
Autores principales: Uehara, Akihito, Motegi, Sei-ichiro, Yamada, Kazuya, Uchiyama, Akihiko, Perera, Buddhini, Toki, Sayaka, Ogino, Sachiko, Yokoyama, Yoko, Takeuchi, Yuko, Ishikawa, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030663/
https://www.ncbi.nlm.nih.gov/pubmed/27650973
http://dx.doi.org/10.1038/srep34012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030663/
https://www.ncbi.nlm.nih.gov/pubmed/27650973
http://dx.doi.org/10.1038/srep34012

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