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Mechanistic insight into the norepinephrine-induced fibrosis in systemic sclerosis
Raynaud’s phenomenon is frequently observed in systemic sclerosis (SSc) patients, and cold- or stress-induced norepinephrine (NE) has been speculated to be associated with vasoconstriction. Objective was to elucidate the role of NE in fibrosis in SSc. IL-6 is a potent stimulator of collagen producti...
Autores principales: | Uehara, Akihito, Motegi, Sei-ichiro, Yamada, Kazuya, Uchiyama, Akihiko, Perera, Buddhini, Toki, Sayaka, Ogino, Sachiko, Yokoyama, Yoko, Takeuchi, Yuko, Ishikawa, Osamu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030663/ https://www.ncbi.nlm.nih.gov/pubmed/27650973 http://dx.doi.org/10.1038/srep34012 |
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