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Rigidity of silicone substrates controls cell spreading and stem cell differentiation

The dependences of spreading and differentiation of stem cells plated on hydrogel and silicone gel substrates on the rigidity and porosity of the substrates have recently been a subject of some controversy. In experiments on human mesenchymal stem cells plated on soft, medium rigidity, and hard sili...

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Detalles Bibliográficos
Autores principales: Vertelov, Grigory, Gutierrez, Edgar, Lee, Sin-Ae, Ronan, Edward, Groisman, Alex, Tkachenko, Eugene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030667/
https://www.ncbi.nlm.nih.gov/pubmed/27651230
http://dx.doi.org/10.1038/srep33411