The PRKD1 promoter is a target of the KRas-NF-κB pathway in pancreatic cancer

Increased expression of PRKD1 and its gene product protein kinase D1 (PKD1) are linked to oncogenic signaling in pancreatic ductal adenocarcinoma, but a direct functional relationship to oncogenic KRas has not been established so far. We here describe the PRKD1 gene promoter as a target for oncogeni...

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Detalles Bibliográficos
Autores principales: Döppler, Heike, Panayiotou, Richard, Reid, Elizabeth M., Maimo, Willibroad, Bastea, Ligia, Storz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030668/
https://www.ncbi.nlm.nih.gov/pubmed/27649783
http://dx.doi.org/10.1038/srep33758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030668/
https://www.ncbi.nlm.nih.gov/pubmed/27649783
http://dx.doi.org/10.1038/srep33758

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