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The PRKD1 promoter is a target of the KRas-NF-κB pathway in pancreatic cancer
Increased expression of PRKD1 and its gene product protein kinase D1 (PKD1) are linked to oncogenic signaling in pancreatic ductal adenocarcinoma, but a direct functional relationship to oncogenic KRas has not been established so far. We here describe the PRKD1 gene promoter as a target for oncogeni...
Autores principales: | Döppler, Heike, Panayiotou, Richard, Reid, Elizabeth M., Maimo, Willibroad, Bastea, Ligia, Storz, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030668/ https://www.ncbi.nlm.nih.gov/pubmed/27649783 http://dx.doi.org/10.1038/srep33758 |
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