Cargando…

Identification of Novel Inhibitors of the Type I Interferon Induction Pathway Using Cell-Based High-Throughput Screening

Production of type I interferon (IFN) is an essential component of the innate immune response against invading pathogens. However, its production must be tightly regulated to avoid harmful effects. Compounds that modulate the IFN response are potentially valuable for a variety of applications due to...

Descripción completa

Detalles Bibliográficos
Autores principales: Gage, Zoe O., Vasou, Andri, Gray, David W., Randall, Richard E., Adamson, Catherine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030734/
https://www.ncbi.nlm.nih.gov/pubmed/27358388
http://dx.doi.org/10.1177/1087057116656314