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Identification of Novel Inhibitors of the Type I Interferon Induction Pathway Using Cell-Based High-Throughput Screening
Production of type I interferon (IFN) is an essential component of the innate immune response against invading pathogens. However, its production must be tightly regulated to avoid harmful effects. Compounds that modulate the IFN response are potentially valuable for a variety of applications due to...
Autores principales: | Gage, Zoe O., Vasou, Andri, Gray, David W., Randall, Richard E., Adamson, Catherine S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030734/ https://www.ncbi.nlm.nih.gov/pubmed/27358388 http://dx.doi.org/10.1177/1087057116656314 |
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