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Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1

Signaling lymphocytic activation molecule (SLAM) family receptors (SFRs) can mediate either activating or inhibitory effects during natural killer cell (NK cell) activation. In this study, we addressed the global role, regulation, and mechanism of action of the SLAM family in NK cells by analyzing a...

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Detalles Bibliográficos
Autores principales: Guo, Huaijian, Cranert, Stacey A., Lu, Yan, Zhong, Ming-Chao, Zhang, Shaohua, Chen, Jun, Li, Rui, Mahl, Sarah E., Wu, Ning, Davidson, Dominique, Waggoner, Stephen N., Veillette, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030809/
https://www.ncbi.nlm.nih.gov/pubmed/27573813
http://dx.doi.org/10.1084/jem.20160552