Translesion Synthesis of the N(2)-2′-Deoxyguanosine Adduct of the Dietary Mutagen IQ in Human Cells: Error-Free Replication by DNA Polymerase κ and Mutagenic Bypass by DNA Polymerases η, ζ, and Rev1

[Image: see text] Translesion synthesis (TLS) of the N(2)-2′-deoxyguanosine (dG-N(2)-IQ) adduct of the carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) was investigated in human embryonic kidney 293T cells by replicating plasmid constructs in which the adduct was individually placed at each g...

Descripción completa

Detalles Bibliográficos
Autores principales: Bose, Arindam, Millsap, Amy D., DeLeon, Arnie, Rizzo, Carmelo J., Basu, Ashis K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031085/
https://www.ncbi.nlm.nih.gov/pubmed/27490094
http://dx.doi.org/10.1021/acs.chemrestox.6b00221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031085/
https://www.ncbi.nlm.nih.gov/pubmed/27490094
http://dx.doi.org/10.1021/acs.chemrestox.6b00221

Ejemplares similares