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Recent advances in T-cell engineering for use in immunotherapy

Adoptive T-cell therapies have shown exceptional promise in the treatment of cancer, especially B-cell malignancies. Two distinct strategies have been used to redirect the activity of ex vivo engineered T cells. In one case, the well-known ability of the T-cell receptor (TCR) to recognize a specific...

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Detalles Bibliográficos
Autores principales: Sharma, Preeti, Kranz, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031132/
https://www.ncbi.nlm.nih.gov/pubmed/27703664
http://dx.doi.org/10.12688/f1000research.9073.1