Cargando…
Protein domain architectures provide a fast, efficient and scalable alternative to sequence-based methods for comparative functional genomics
A functional comparative genome analysis is essential to understand the mechanisms underlying bacterial evolution and adaptation. Detection of functional orthologs using standard global sequence similarity methods faces several problems; the need for defining arbitrary acceptance thresholds for simi...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031134/ https://www.ncbi.nlm.nih.gov/pubmed/27703668 http://dx.doi.org/10.12688/f1000research.9416.3 |