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Protein domain architectures provide a fast, efficient and scalable alternative to sequence-based methods for comparative functional genomics

A functional comparative genome analysis is essential to understand the mechanisms underlying bacterial evolution and adaptation. Detection of functional orthologs using standard global sequence similarity methods faces several problems; the need for defining arbitrary acceptance thresholds for simi...

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Detalles Bibliográficos
Autores principales: Koehorst, Jasper J., Saccenti, Edoardo, Schaap, Peter J., Martins dos Santos, Vitor A. P., Suarez-Diez, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031134/
https://www.ncbi.nlm.nih.gov/pubmed/27703668
http://dx.doi.org/10.12688/f1000research.9416.3