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Protein domain architectures provide a fast, efficient and scalable alternative to sequence-based methods for comparative functional genomics
A functional comparative genome analysis is essential to understand the mechanisms underlying bacterial evolution and adaptation. Detection of functional orthologs using standard global sequence similarity methods faces several problems; the need for defining arbitrary acceptance thresholds for simi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
F1000Research
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031134/ https://www.ncbi.nlm.nih.gov/pubmed/27703668 http://dx.doi.org/10.12688/f1000research.9416.3 |