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Prion pathogenesis is unaltered following down-regulation of SIGN-R1
Prion diseases are infectious neurodegenerative disorders characterised by accumulations of abnormal prion glycoprotein in affected tissues. Following peripheral exposure, many prion strains replicate upon follicular dendritic cells (FDC) in lymphoid tissues before infecting the brain. An intact spl...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031137/ https://www.ncbi.nlm.nih.gov/pubmed/27522473 http://dx.doi.org/10.1016/j.virol.2016.08.005 |