Allosteric Optical Control of a Class B G‐Protein‐Coupled Receptor

Allosteric regulation promises to open up new therapeutic avenues by increasing drug specificity at G‐protein‐coupled receptors (GPCRs). However, drug discovery efforts are at present hampered by an inability to precisely control the allosteric site. Herein, we describe the design, synthesis, and te...

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Detalles Bibliográficos
Autores principales: Broichhagen, Johannes, Johnston, Natalie R., von Ohlen, Yorrick, Meyer‐Berg, Helena, Jones, Ben J., Bloom, Stephen R., Rutter, Guy A., Trauner, Dirk, Hodson, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031193/
https://www.ncbi.nlm.nih.gov/pubmed/27059784
http://dx.doi.org/10.1002/anie.201600957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031193/
https://www.ncbi.nlm.nih.gov/pubmed/27059784
http://dx.doi.org/10.1002/anie.201600957

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